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Medical Xpress Ophthalmology News Feed

  • Researchers find that nicotinamide may help treat fibrotic eye diseases and mitigate vision lossResearchers find that nicotinamide may help treat fibrotic eye diseases and mitigate vision loss
    Nicotinamide, a form of vitamin B3, can inhibit aggressive cell transformations during wound healing and may be key to the development of therapies to treat fibrotic eye diseases that impair vision, according to a new Mount Sinai study published on Thursday, April 2, in Stem Cell Reports. Read more »
  • Researchers discover genetic processes that determine short-sightednessResearchers discover genetic processes that determine short-sightedness
    Three previously unknown genetic mechanisms have been discovered in causing myopia otherwise known as short or near-sightedness, finds a new study. Read more »
  • Advances in production of retinal cells for treating blindnessAdvances in production of retinal cells for treating blindness
    Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using CRISPR/Cas9 gene editing, they also modified the cells so that they can hide from the immune system to prevent rejection. The studies are published in the scientific journals Nature Communications and Stem Cell Reports. Read more »
  • Lipid helps heal the eye's frontline protectionLipid helps heal the eye's frontline protection
    A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report. Read more »
  • Immunological regulatory circuit may play central role in ocular diseasesImmunological regulatory circuit may play central role in ocular diseases
    Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cell, those that line the interior of blood vessels. The discovery was made by analyzing gene expression in 8000 cells of the choroid, the vascular layer at the rear of the eye between the retina and the sclera. The results, published today in the Journal of Experimental Medicine, open… Read more »
  • Researchers discover tooth-enamel protein in eyes with dry AMDResearchers discover tooth-enamel protein in eyes with dry AMD
    A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI). This protein, amelotin, may turn out to be a therapeutic target for the blinding disease. The findings were published in the journal Translational Research. NEI is part of the National Institutes of Health. Read more »
  • Modern virtual and augmented reality device can help simulate sight lossModern virtual and augmented reality device can help simulate sight loss
    Published today, during World Glaucoma Week 2020, a new study demonstrates how commercially available head mounted displays (HMD) can be used to simulate the day-to-day challenges faced by people with glaucoma. Read more »
  • Ultra-wide field retinal imaging techniques cannot be used interchangeablyUltra-wide field retinal imaging techniques cannot be used interchangeably
    Diabetic retinopathy can be diagnosed and graded with the use of a newer scanning technology called ultra-wide field (UWF) imaging, a system that generates high-quality pictures showing most of the retina. Research from the Joslin Diabetes Center's Beetham Eye Institute has now shown that one technique, UFW fluorescein angiography, detects over three times more microaneurysms than UWF color imaging, suggesting that the two modalities should not be used interchangeably when evaluating and treating this vision-threatening condition. The research is published… Read more »
  • AI may help spot newborns at risk for most severe form of blinding diseaseAI may help spot newborns at risk for most severe form of blinding disease
    An artificial intelligence (AI) device that has been fast-tracked for approval by the Food and Drug Administration may help identify newborns at risk for aggressive posterior retinopathy of prematurity (AP-ROP). AP-ROP is the most severe form of ROP and can be difficult to diagnose in time to save vision. The findings of the National Eye Institute-funded study published online February 7 in Ophthalmology. Read more »
  • New discovery has important implications for treating common eye diseaseNew discovery has important implications for treating common eye disease
    Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness. Read more »
  • Research team delivers breakthrough for leading cause of blindnessResearch team delivers breakthrough for leading cause of blindness
    Researchers have identified a new protein linked to age-related macular degeneration (AMD) that could offer new hope for the diagnosis and treatment of the disease, which affects over 1.5 million people in the UK alone. Read more »
  • Artificial intelligence predicts treatment outcome for diabetes-related vision lossArtificial intelligence predicts treatment outcome for diabetes-related vision loss
    A new approach that uses artificial intelligence to analyze retinal images could one day help doctors select the best treatment for patients with vision loss from diabetic macular edema. This diabetes complication is a major cause of vision loss among working-age adults. Read more »
  • Potential way to halt blinding macular degeneration identifiedPotential way to halt blinding macular degeneration identified
    Researchers have successfully treated age-related macular degeneration (AMD) in mice after finding an unexpected link between the two main forms of the blinding eye disease, the leading cause of vision loss in people 60 and older. Read more »
  • New drug candidate is promising therapeutic option for angiogenic retinal diseasesNew drug candidate is promising therapeutic option for angiogenic retinal diseases
    A research team led by scientists at Beth Israel Deaconess Medical Center (BIDMC) and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases. Read more »
  • Study stops vision loss in late-stage canine X-linked retinitis pigmentosaStudy stops vision loss in late-stage canine X-linked retinitis pigmentosa
    Three years ago, a team from the University of Pennsylvania announced that they had cured X-linked retinitis pigmentosa, a blinding retinal disease, in dogs. Now they've shown that they can cure the canine disease over the long term, even when the treatment is given after half or more of the affected photoreceptor cells have been destroyed. Read more »
  • Carrots do help aging eyes, study showsCarrots do help aging eyes, study shows
    (HealthDay)—Your parents may have told you, "Eat your carrots, they're good for your eyes," and a new study suggests they were on to something. Read more »
  • Scientists test new gene therapy for vision loss from a mitochondrial diseaseScientists test new gene therapy for vision loss from a mitochondrial disease
    Researchers funded by the National Institutes of Health have developed a novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON), and found that they can use gene therapy to improve visual function in the mice. LHON is one of many diseases tied to gene mutations that damage the tiny energy factories that power our cells, called mitochondria. Read more »
  • 'Hardwired' focus may explain eyesight problems for premature babies later in life'Hardwired' focus may explain eyesight problems for premature babies later in life
    Babies born slightly earlier are more at risk of vision problems later in life due to subtle differences in their eye development, a new University of Reading study has found. Read more »
  • Diet, exercise, smoking habits and genes interact to affect AMD riskDiet, exercise, smoking habits and genes interact to affect AMD risk
    People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of heavy smoking and consistently did not exercise or eat enough fruits and vegetables, according to an observational study of women funded by the National Eye Institute, part of the National Institutes of Health. Read more »
  • Scientists move closer to curing common eye disorderScientists move closer to curing common eye disorder
    Scientists at the University of Manchester have successfully restored the sight of laboratory mice suffering from a common cause of blindness in people. Read more »
  • Vitamin D may play key role in preventing macular degeneration
    Vitamin D has been studied extensively in relation to bone health as well as cancer. Now, a team led by a researcher at the University at Buffalo has discovered that vitamin D may play a significant role in eye health, specifically in the possible prevention of age-related macular degeneration, or AMD, among women who are more genetically prone to developing the sight-damaging disease. Read more »
  • New clues found to vision loss in macular degeneration?New clues found to vision loss in macular degeneration?
    Scientists have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration. Read more »
  • What would the world look like to someone with a bionic eye?What would the world look like to someone with a bionic eye?
    Various sight recovery therapies are being developed by companies around the world, offering new hope for people who are blind. But little is known about what the world will look like to patients who undergo those procedures. Read more »
  • Eye drop gives hope for knifeless cataract cureEye drop gives hope for knifeless cataract cure
    An eye drop tested on dogs suggests that cataracts, the most common cause of blindness in humans, could one day be cured without surgery, a study said Wednesday. Read more »
  • Surprisingly rapid regrowth of unused brain connections after decades of near blindnessSurprisingly rapid regrowth of unused brain connections after decades of near blindness
    Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP), have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine. Read more »
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